Method for predicting RNA secondary structure.
نویسندگان
چکیده
منابع مشابه
New Method for Predicting RNA Secondary Structure
It has become clear recently that there are many RNAs that are not translated into proteins, instead they work as functional molecules. These RNAs are called “non-coding RNAs.” Predicting the secondary structure of these RNAs is important for understanding their functions. We will therefore focus on Nussinov’s algorithm and the SCFG version of Nussinov’s algorithm as useful techniques for predi...
متن کاملMethod for predicting RNA secondary structure.
We report a method for predicting the most stable secondary structure of RNA from its primary sequence of nucleotides. The technique consists of a series of three computer programs interfaced to take the nucleotide sequence of any RNA and (a) list all possible helical regions, using modified Watson-Crick base-pairing rules; (b) create all possible secondary structures by forming permutations of...
متن کاملA New Method for Predicting RNA Secondary Structure
It has become clear recently that there are many RNAs that are not translated into proteins, instead they work as functional molecules. These RNAs are called “non-coding RNAs.” Predicting the secondary structure of these RNAs is important for understanding their functions. We focus on Nussinov’s algorithm and the SCFG version of Nussinov’s algorithm as useful techniques for predicting RNA secon...
متن کاملPrinciples for Predicting RNA Secondary Structure Design Difficulty.
Designing RNAs that form specific secondary structures is enabling better understanding and control of living systems through RNA-guided silencing, genome editing and protein organization. Little is known, however, about which RNA secondary structures might be tractable for downstream sequence design, increasing the time and expense of design efforts due to inefficient secondary structure choic...
متن کاملA classifier system for predicting RNA secondary structure
Finding the secondary structures of ribonucleic acid sequences is a very important task. The secondary structure helps determine their functionalities which in turn plays a role in the proteins production. Manual laboratory methods use X-ray diffraction to predict secondary structures but it is complex, slow and expensive. Therefore, different computational approaches are used to predict RNA se...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1975
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.72.6.2017